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Isotretinoin: what active ingredients are incompatible with this treatment? – Pharmaceutical Post – Todo Dermo

In Beauty

The isotretinoin is a retinoid that is prescribed for the treatment of acne moderate or severe being very effective but side effects. This is indicated to TodoDermo Maria Luisa Bertomeu, member of Dermopharmacy the COF of Valencia: “This is a very effective drug but be very present possible contraindications”. In this regard, Raquel Novo, head of the Department of Dermatology at University Hospital HM Puerta del Sur and HM Montepríncipe of Madrid, explains that isotretinoin incompatibilities primarily with two groups of active ingredients : “The tetracyclines, belonging to a group of antibiotics very used to treat skin diseasesAnd vitamin A or vitamin supplement that contains it. “

  • “Avoid retinol creams and alpha or beta hydroxyacids, such as glycolic acid and salicylic”

This expert remembers that “-the tetraciclinas- incompatible antibiotics are not related to the drugs prescribed for diseases of the airways”, but in any case discourages “self – medication during therapy.” To these considerations, Eduardo Bran Lopez, Chief of Dermatology Hospital Clínico San Carlos de Madrid, adds that “Antacids may decrease the absorption of isotretinoin if ingested simultaneously” . To avoid this , Lopez recommends taking antacids “with a separation interval of more than two hours.”

On the use of compounds with vitamin A, both dermatologists agree that might occur hypervitaminosis overdosage. Apart from these interactions, Novo said that “isotretinoin is metabolized in the liver, so you should limit other medications or substances that can impair liver function.”

Isotretinoin and COSMETICS

This acne treatment has no contraindications such as cosmetic compounds but, due to changes in the skin, it is appropriate to use specific products . “Reduce sebaceous gland secretion and dry, which increases the dryness of the skin and makes it more sensitive to aggressive active ingredients” details Novo. In their experience, he considered “generically be avoided retinol creams and alpha or beta hydroxyacids, such as glycolic acid and salicylic”.

To counter these effects, vocal Dermopharmacy Valencia COF suggests “the use of moisturizing lotion with shea butter and gotu kola , the latter ingredient with healing properties. For the shower it is better to use soaps without detergents and, with dry skin, apply aloe vera “. Bertomeu insist on the need to care for lips and eyes: “To combat dry eyes, especially if the patient wears contact lenses, eye drops should be administered with hyaluronic acid without preservatives”.

Other necessary measures for self – care during isotretinoin are “the use of sunscreens to 50+ factor and without any action involving an attack as waxing or laser, massages are horsehair gloves and face brushes” Novo lists.


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